Methanol → N-{3-[1-(2-fluoro-4-iodophenyl)-3-(4-methoxybenzyl)-6,8-dimethyl-2,4,7-trioxo-1,2,3,4,7,8-hexahydropyrido[2,3-d]pyrimidin-5-ylamino]-phenyl}-acetamide
Reaction equation
[CH3:52][N:53]([CH3:54])[C:55](=[O:56])[CH3:57].[CH3:66][OH:67].[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:40])[n:11]([CH2:31][c:32]3[cH:33][cH:34][c:35]([O:38][CH3:39])[cH:36][cH:37]3)[c:12](=[O:30])[c:13]3[c:14]2[n:15]([CH3:29])[c:16](=[O:28])[c:17]([CH3:27])[c:18]3[O:19][S:20]([C:21]([F:22])([F:23])[F:24])(=[O:25])=[O:26])[cH:4][cH:5][c:6]([I:8])[cH:7]1.[NH2:41][c:42]1[cH:43][c:44]([NH:45][C:46]([CH3:47])=[O:48])[cH:49][cH:50][cH:51]1.[n:58]1[c:59]([CH3:60])[cH:61][cH:62][cH:63][c:64]1[CH3:65]>>[F:1][c:2]1[c:3](-[n:9]2[c:10](=[O:40])[n:11]([CH2:31][c:32]3[cH:33][cH:34][c:35]([O:38][CH3:39])[cH:36][cH:37]3)[c:12](=[O:30])[c:13]3[c:14]2[n:15]([CH3:29])[c:16](=[O:28])[c:17]([CH3:27])[c:18]3[NH:41][c:42]2[cH:43][c:44]([NH:45][C:46]([CH3:47])=[O:48])[cH:49][cH:50][cH:51]2)[cH:4][cH:5][c:6]([I:8])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-d50e0216b2934a0888df904b0c9d8325
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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