Ethanol → Ethyl 1-benzylpiperidine-4-carboxylate

HRID 1231361Notes

Reaction equation

HRID 1231361 reaction equation
[C:20](=[O:21])([O-:22])[O-:23].[C:30]([O:31][CH2:32][CH3:33])(=[O:34])[CH3:35].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][NH:9][CH2:10][CH2:11]1.[CH3:26][CH2:27][OH:28].[Cl:12][CH2:13][c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1.[K+:24].[K+:25].[OH2:29]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][N:9]([CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:10][CH2:11]1

Participants

8

Reactant 7

HCID 702EthanolHCID 813Potassium Cation2×HCID 962WaterHCID 7503Benzyl ChlorideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 70770Ethyl 4-piperidinecarboxylate

Product 1

HCID 90423Ethyl 1-benzylpiperidine-4-carboxylate

Sources & evidence

ORD record
ord-ac8d04bfd9bc42c3bfa5a60a35441d3c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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