Phthalimide → 2-(5,7-Difluoroquinolin-6-ylmethyl)isoindoline-1,3-dione
Reaction equation
[C:48]1(=[O:58])[NH:49][C:50](=[O:57])[c:51]2[cH:52][cH:53][cH:54][cH:55][c:56]21.[CH2:59]1[O:60][CH2:61][CH2:62][CH2:63]1.[F:34][c:35]1[c:36]2[cH:37][cH:38][cH:39][n:40][c:41]2[cH:42][c:43]([F:47])[c:44]1[CH2:45][OH:46].[N:1]([C:2]([O:3][CH:4]([CH3:5])[CH3:6])=[O:7])=[N:8][C:9]([O:10][CH:11]([CH3:12])[CH3:13])=[O:14].[c:15]1([P:16]([c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[cH:29][cH:30][cH:31][cH:32][cH:33]1>>[F:34][c:35]1[c:36]2[cH:37][cH:38][cH:39][n:40][c:41]2[cH:42][c:43]([F:47])[c:44]1[CH2:45][N:49]1[C:48](=[O:58])[c:56]2[c:51]([cH:52][cH:53][cH:54][cH:55]2)[C:50]1=[O:57]Participants
6
Sources & evidence
- ORD record
- ord-f1dd226fc248452b9992c41bd559fc7d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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