Chloride → benzyl 3-[[3,6-diethyl-5-[6-methoxy-2-(trifluoromethyl)-3-pyridinyl]pyrazin-2-yl]amino]-4-ethoxypyrrolidine-1-carboxylate
Reaction equation
[C:14]([Li:15])([CH3:16])([CH3:17])[CH3:18].[C:49](=[O:50])([OH:51])[O-:52].[CH2:19]([CH3:20])[c:21]1[c:22]([NH:30][CH:31]2[CH2:32][N:33]([C:39](=[O:40])[O:41][CH2:42][c:43]3[cH:44][cH:45][cH:46][cH:47][cH:48]3)[CH2:34][CH:35]2[O:36][CH2:37][CH3:38])[n:23][c:24]([CH2:28][CH3:29])[c:25]([I:27])[n:26]1.[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[Cl-:59].[Cl-:61].[I:1][c:2]1[c:3]([C:10]([F:11])([F:12])[F:13])[n:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1.[Na+:53].[Zn+2:60]>>[c:2]1(-[c:25]2[c:24]([CH2:28][CH3:29])[n:23][c:22]([NH:30][CH:31]3[CH2:32][N:33]([C:39](=[O:40])[O:41][CH2:42][c:43]4[cH:44][cH:45][cH:46][cH:47][cH:48]4)[CH2:34][CH:35]3[O:36][CH2:37][CH3:38])[c:21]([CH2:19][CH3:20])[n:26]2)[c:3]([C:10]([F:11])([F:12])[F:13])[n:4][c:5]([O:8][CH3:9])[cH:6][cH:7]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-01187c33170c4158bf94037cac95d606
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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