Phthalimide → Ethyl 4-(1,3-dioxoisoindolin-2-yl)-1-methylcyclohexanecarboxylate

HRID 1234797Notes

Reaction equation

HRID 1234797 reaction equation
[CH2:58]1[O:59][CH2:60][CH2:61][CH2:62]1.[O:33]=[C:34]1[NH:35][C:36](=[O:37])[c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]21.[O:44]=[C:45]([O:46][CH:47]([CH3:48])[CH3:49])[N:50]=[N:51][C:52]([O:53][CH:54]([CH3:55])[CH3:56])=[O:57].[OH:1][CH:2]1[CH2:3][CH2:4][C:5]([C:8](=[O:9])[O:10][CH2:11][CH3:12])([CH3:13])[CH2:6][CH2:7]1.[c:14]1([P:15]([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[CH:2]1([N:35]2[C:34](=[O:33])[c:43]3[c:38]([cH:39][cH:40][cH:41][cH:42]3)[C:36]2=[O:37])[CH2:3][CH2:4][C:5]([C:8](=[O:9])[O:10][CH2:11][CH3:12])([CH3:13])[CH2:6][CH2:7]1

Participants

6

Reactant 5

HCID 6809PhthalimideHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 58230927Ethyl 4-hydroxy-1-methylcyclohexanecarboxylate

Product 1

HCID 58074352Ethyl 4-(1,3-dioxoisoindolin-2-yl)-1-methylcyclohexanecarboxylate

Sources & evidence

ORD record
ord-bbc918f75c1b41cbb0ea445bd022556c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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