Hydrochloric Acid → 6-CHLORO-N-[5-(2-CYCLOPENTYLAMINO-4-PYRIDYL)-4-(3-METHYLPHENYL)-1,3-THIAZOL-2-YL]NICOTINAMIDE

HRID 1234799Notes

Reaction equation

HRID 1234799 reaction equation
[C:37](=[O:38])([O-:39])[OH:40].[CH3:42][N:43]([CH3:44])[c:45]1[cH:46][cH:47][n:48][cH:49][cH:50]1.[CH3:51][N:52]([CH3:53])[C:54](=[O:55])[CH3:56].[CH:1]1([NH:6][c:7]2[n:8][cH:9][cH:10][c:11](-[c:13]3[c:14](-[c:19]4[cH:20][c:21]([CH3:25])[cH:22][cH:23][cH:24]4)[n:15][c:16]([NH2:18])[s:17]3)[cH:12]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[Cl:27][c:28]1[n:29][cH:30][c:31]([C:32](=[O:33])[Cl:34])[cH:35][cH:36]1.[ClH:26].[Na+:41]>>[CH:1]1([NH:6][c:7]2[n:8][cH:9][cH:10][c:11](-[c:13]3[c:14](-[c:19]4[cH:20][c:21]([CH3:25])[cH:22][cH:23][cH:24]4)[n:15][c:16]([NH:18][C:32]([c:31]4[cH:30][n:29][c:28]([Cl:27])[cH:36][cH:35]4)=[O:33])[s:17]3)[cH:12]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 923Sodium ionHCID 142844-(Dimethylamino)pyridineHCID 31374DimethylacetamideHCID 27821656-Chloronicotinoyl ChlorideHCID 17862984HCID 17862984, compound

Product 1

HCID 102066296-CHLORO-N-[5-(2-CYCLOPENTYLAMINO-4-PYRIDYL)-4-(3-METHYLPHENYL)-1,3-THIAZOL-2-YL]NICOTINAMIDE

Sources & evidence

ORD record
ord-132524a4b0b94247833a82f9a27bd720
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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