Tetrahydrofuran → 2-tert-butyl-4-chloro-5-[4-(3-hydroxybutyl)benzyloxy]-2H-pyridazin-3-one
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[n:5]1[n:6][cH:7][c:8]([OH:13])[c:9]([Cl:12])[c:10]1=[O:11].[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[CH3:65][CH2:66][O:67][C:68](=[O:69])[CH3:70].[O:46]=[C:47]([O:48][CH:49]([CH3:50])[CH3:51])[N:52]=[N:53][C:54]([O:55][CH:56]([CH3:57])[CH3:58])=[O:59].[OH:14][CH2:15][c:16]1[cH:17][cH:18][c:19]([CH2:22][CH2:23][CH:24]([CH3:25])[OH:26])[cH:20][cH:21]1.[c:27]1([P:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:41][cH:42][cH:43][cH:44][cH:45]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[n:5]1[n:6][cH:7][c:8]([O:13][CH2:15][c:16]2[cH:17][cH:18][c:19]([CH2:22][CH2:23][CH:24]([CH3:25])[OH:26])[cH:20][cH:21]2)[c:9]([Cl:12])[c:10]1=[O:11]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5635419b9b6d4479904e1fb813f66c91
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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