Hydrochloric Acid → 3-(6-tert-Butyl-4-trifluoromethyl-pyridin-3-yl)-N-(3-ethynyl-5-fluoro-4-methanesulfonylamino-benzyl)-acrylamide
Reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[c:22]1[cH:23][c:24]([C:33]([F:34])([F:35])[F:36])[c:25]([CH:28]=[CH:29][C:30](=[O:31])[OH:32])[cH:26][n:27]1.[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:37][N:38]1[CH2:39][CH2:40][CH2:41][C:42]1=[O:43].[ClH:17].[NH2:1][CH2:2][c:3]1[cH:4][c:5]([C:15]#[CH:16])[c:6]([NH:10][S:11](=[O:12])(=[O:13])[CH3:14])[c:7]([F:9])[cH:8]1>>[NH:1]([CH2:2][c:3]1[cH:4][c:5]([C:15]#[CH:16])[c:6]([NH:10][S:11](=[O:12])(=[O:13])[CH3:14])[c:7]([F:9])[cH:8]1)[C:30]([CH:29]=[CH:28][c:25]1[c:24]([C:33]([F:34])([F:35])[F:36])[cH:23][c:22]([C:18]([CH3:19])([CH3:20])[CH3:21])[n:27][cH:26]1)=[O:31]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a768310ef9b3407994fb10013aab13cb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…