Triethylamine → {1-[6-Fluoro-4-(2-{5-fluoro-2-[2-(2-oxo-2,3-dihydro-imidazol-1-yl)-ethylamino]-pyrimidin-4-yl}-benzo[b]thiophen-7-yl)-pyridin-3-yl]-ethyl}-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH3:9])[c:10]1[cH:11][n:12][c:13]([F:33])[cH:14][c:15]1-[c:16]1[cH:17][cH:18][cH:19][c:20]2[c:21]1[s:22][c:23](-[c:25]1[n:26][c:27]([Cl:32])[n:28][cH:29][c:30]1[F:31])[cH:24]2)=[O:34].[CH3:44][CH2:45][N:46]([CH2:47][CH3:48])[CH2:49][CH3:50].[CH3:51][N:52]1[CH2:53][CH2:54][CH2:55][C:56]1=[O:57].[CH3:58][CH2:59][O:60][C:61](=[O:62])[CH3:63].[NH2:35][CH2:36][CH2:37][n:38]1[c:39](=[O:43])[nH:40][cH:41][cH:42]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]([CH3:9])[c:10]1[cH:11][n:12][c:13]([F:33])[cH:14][c:15]1-[c:16]1[cH:17][cH:18][cH:19][c:20]2[c:21]1[s:22][c:23](-[c:25]1[n:26][c:27]([NH:35][CH2:36][CH2:37][n:38]3[c:39](=[O:43])[nH:40][cH:41][cH:42]3)[n:28][cH:29][c:30]1[F:31])[cH:24]2)=[O:34]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-a0883a02e1844c2d8daed4e0387a985b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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