Methanol → 6-Bromo-4-(2-morpholinoethyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one
Reaction equation
[Br:1][c:2]1[c:3]([NH:9][C:10]([CH2:11][I:12])=[O:13])[n:4][cH:5][c:6]([Br:8])[n:7]1.[CH3:32][OH:33].[CH3:34][C:35]#[N:36].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[CH:14]([N:15]([CH:16]([CH3:17])[CH3:18])[CH2:19][CH3:20])([CH3:21])[CH3:22].[O:23]1[CH2:24][CH2:25][N:26]([CH2:29][CH2:30][NH2:31])[CH2:27][CH2:28]1>>[c:2]12[c:3]([n:4][cH:5][c:6]([Br:8])[n:7]1)[NH:9][C:10](=[O:13])[CH2:11][N:31]2[CH2:30][CH2:29][N:26]1[CH2:25][CH2:24][O:23][CH2:28][CH2:27]1Participants
7
Sources & evidence
- ORD record
- ord-caa22831b9644bf2ad185fdc72aa108e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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