Cyanide → 2-(Morpholin-4-yl)-3-trifluoromethyl-5-cyanopyridine
Reaction equation
[C-:25]#[N:26].[C-:28]#[N:29].[CH3:18][N:19]1[CH2:20][CH2:21][CH2:22][C:23]1=[O:24].[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[n:8][cH:9][c:10]([Br:17])[cH:11][c:12]2[C:13]([F:14])([F:15])[F:16])[CH2:5][CH2:6]1.[O:32]=[C:33]([CH:34]=[CH:35][c:36]1[cH:37][cH:38][cH:39][cH:40][cH:41]1)[CH:42]=[CH:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[O:50]=[C:51]([CH:52]=[CH:53][c:54]1[cH:55][cH:56][cH:57][cH:58][cH:59]1)[CH:60]=[CH:61][c:62]1[cH:63][cH:64][cH:65][cH:66][cH:67]1.[O:68]=[C:69]([CH:70]=[CH:71][c:72]1[cH:73][cH:74][cH:75][cH:76][cH:77]1)[CH:78]=[CH:79][c:80]1[cH:81][cH:82][cH:83][cH:84][cH:85]1.[Pd:30].[Pd:31].[Zn+2:27]>>[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[n:8][cH:9][c:10]([C:18]#[N:19])[cH:11][c:12]2[C:13]([F:14])([F:15])[F:16])[CH2:5][CH2:6]1Participants
7
Sources & evidence
- ORD record
- ord-641db9b62ef74f49b15130689f67b6d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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