1,2-Dichloroethane → N-[2-(Benzyloxy)ethyl]-N-(4-{[tert-butyl(dimethyl)silyl]oxy}butyl)-6-(3-chloro-4-fluorobenzyl)-4-methoxy-3,5-dioxo-2,3,5,6,7,8-hexahydro-2,6-naphthyridine-1-carboxamide
Reaction equation
[CH2:27]([c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[O:34][CH2:35][CH2:36][NH:37][CH2:38][CH2:39][CH2:40][CH2:41][O:42][Si:43]([CH3:44])([CH3:45])[C:46]([CH3:47])([CH3:48])[CH3:49].[CH2:50]([Cl:51])[CH2:52][Cl:53].[CH:64]([N:65]([CH:66]([CH3:67])[CH3:68])[CH2:69][CH3:70])([CH3:71])[CH3:72].[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:22])[c:8]3[c:9]([O:20][CH3:21])[c:10](=[O:19])[nH:11][c:12]([C:16](=[O:17])[OH:18])[c:13]3[CH2:14][CH2:15]2)[cH:23][cH:24][c:25]1[F:26].[O:73]=[CH:74][N:75]([CH3:76])[CH3:77].[OH:54][n:55]1[c:56]2[n:57][cH:58][cH:59][cH:60][c:61]2[n:62][n:63]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][N:6]2[C:7](=[O:22])[c:8]3[c:9]([O:20][CH3:21])[c:10](=[O:19])[nH:11][c:12]([C:16](=[O:18])[N:37]([CH2:36][CH2:35][O:34][CH2:27][c:28]4[cH:29][cH:30][cH:31][cH:32][cH:33]4)[CH2:38][CH2:39][CH2:40][CH2:41][O:42][Si:43]([CH3:44])([CH3:45])[C:46]([CH3:47])([CH3:48])[CH3:49])[c:13]3[CH2:14][CH2:15]2)[cH:23][cH:24][c:25]1[F:26]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-7a2a780e13e7408da734ed962d6d19f3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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