Dimethylformamide → N1-(3-Fluoro-4-(pyrrolo[2,1-f][1,2,4]triazin-4-yloxy)phenyl)-N3-(4-fluorophenyl)malonamide
Reaction equation
[CH3:31][N:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1.[CH3:46][N:47]([CH3:48])[CH:49]=[O:50].[CH3:51][CH2:52][O:53][C:54]([CH3:55])=[O:56].[F:1][c:2]1[cH:3][c:4]([NH:18][C:19]([CH2:20][C:21](=[O:22])[NH:23][c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)=[O:30])[cH:5][cH:6][c:7]1[O:8][c:9]1[n:10][cH:11][n:12][n:13]2[c:14]1[cH:15][cH:16][cH:17]2.[NH2:38][c:39]1[cH:40][cH:41][c:42]([F:43])[cH:44][cH:45]1>>[F:1][c:2]1[cH:3][c:4]([NH:18][C:19]([CH2:20][C:21](=[O:22])[NH:23][c:24]2[cH:25][cH:26][c:27]([F:43])[cH:28][cH:29]2)=[O:30])[cH:5][cH:6][c:7]1[O:8][c:9]1[n:10][cH:11][n:12][n:13]2[c:14]1[cH:15][cH:16][cH:17]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c54e9a06837a4738bd896505e7bea21e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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