Chloride → methyl 4-(tert-butoxycarbonyl)-5-(4-chlorophenyl)-6-cyclohexyl-4H-thieno[3,2-b]pyrrole-2-carboxylate
Reaction equation
[Br:1][c:2]1[c:3]([CH:21]2[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]2)[c:4]2[c:5]([n:6]1[C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[cH:14][c:15]([C:17](=[O:18])[O:19][CH3:20])[s:16]2.[C:39](=[O:40])([O-:41])[O-:42].[CH3:45][CH2:46][OH:47].[CH3:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1.[CH3:55][CH2:56][O:57][C:58]([CH3:59])=[O:60].[Cl-:37].[Cl:27][c:28]1[cH:29][cH:30][c:31]([B:34]([OH:35])[OH:36])[cH:32][cH:33]1.[Li+:38].[Na+:43].[Na+:44].[cH:61]1[cH:62][cH:63][c:64]([P:65]([Pd:66]([P:67]([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)([c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)([P:86]([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)([c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)[P:105]([c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)([c:112]2[cH:113][cH:114][cH:115][cH:116][cH:117]2)[c:118]2[cH:119][cH:120][cH:121][cH:122][cH:123]2)([c:124]2[cH:125][cH:126][cH:127][cH:128][cH:129]2)[c:130]2[cH:131][cH:132][cH:133][cH:134][cH:135]2)[cH:136][cH:137]1>>[c:2]1(-[c:31]2[cH:30][cH:29][c:28]([Cl:27])[cH:33][cH:32]2)[c:3]([CH:21]2[CH2:22][CH2:23][CH2:24][CH2:25][CH2:26]2)[c:4]2[c:5]([n:6]1[C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[cH:14][c:15]([C:17](=[O:18])[O:19][CH3:20])[s:16]2Participants
11
Reactant 10
HCID 312Chloride
HCID 702Ethanol
HCID 923Sodium ion2×
HCID 1140Toluene
HCID 8857Ethyl Acetate
HCID 19660Carbonate Ion
HCID 28486Lithium ion
HCID 742994-Chlorophenylboronic acid
HCID 67298537methyl 5-bromo-4-(tert-butoxycarbonyl)-6-cyclohexyl-4H-thieno[3,2-b]pyrrole-2-carboxylate
HCID 178420554HCID 178420554, compoundProduct 1
Sources & evidence
- ORD record
- ord-3b822a6557074a6aafb97bfc155dbfc6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…