反应详情

A solution of N1-cyclohexylmethyl-5-(4-methyl-piperazin-1-yl)-N4-phenyl-benzene-1,2,4-triamine (0.10 g, 0.25 mmol) and 1,1′-carbonyldiimidazole (0.12 g, 0.76 mmol) in THF (3 mL) was stirred at room temperature for 17.5 h. The solvent was evaporated and the resulting residue was chromatographed (FCC, 5% MeOH/CH2Cl2) to give the title compound as a white solid (0.07 g, 61.6% yield). M+, 420.

1. customThe solvent was evaporated
2. customthe resulting residue was chromatographed (FCC, 5% MeOH/CH2Cl2)