反应详情

75 g (0.15 mol) of 1-(2-fluoro-6-iodo-4-methylphenyl)-2-(4′-propyl-bicyclohexyl-4-yl)-prop-2-en-1-ol, 50 ml of triethylamine, 400 mg of palladium(II) acetate (1.8 mmol) and 960 mg (3.7 mmol) of triphenylphosphine are dissolved in 200 ml of acetonitrile and refluxed overnight. The mixture is cooled down to room temperature and subjected to conventional workup.

1. temperaturerefluxed overnight