Triphenylphosphine → HCID 178444493, compound

HRID 1249310Notes

Reaction equation

HRID 1249310 reaction equation
[Br:1][CH2:2][CH2:3][C@H:4]1[CH2:9][CH2:8][C@H:7]([CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[CH2:6][CH2:5]1.[C:15]1([P:21]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C1(C)C(C)=CC=CC=1>[Br-:1].[CH2:10]([C@H:7]1[CH2:8][CH2:9][C@H:4]([CH2:3][CH2:2][P+:21]([C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH2:5][CH2:6]1)[CH2:11][CH2:12][CH2:13][CH3:14]

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 178444391HCID 178444391, compound

Product 1

HCID 178444493HCID 178444493, compoundYield 57.6%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Conditions

Temperature
5 °C

Procedure

A mixture of 13.0 g of 1-bromo-2-(trans-4-pentylcyclohexyl)ethane, 16.0 g of triphenylphosphine and 375 ml of xylene was heated to boiling for 60 hours. After cooling to 5° C., the precipitated product was filtered off under suction, washed with toluene and hexane and dried, there being obtained 15.0 g of 2-(trans-4-pentylcyclohexyl)ethyl-triphenylphosphonium bromide; m.p. 183°-185° C.

Workup

  1. temperaturewas heated
  2. filtrationthe precipitated product was filtered off under suction
  3. washwashed with toluene and hexane
  4. customdried

Sources & evidence

ORD record
ord-2f72dcc3ed3b40bbbac204edef6a2d0e
Source dataset
uspto-grants-1986_12
Patent number
US04630896

Reaction notes

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