反应详情

Ethyl acetate saturated with gaseous HCl (50 ml) was added to a solution of 1-tert-butoxycarbonyl-4-[4-(4-pyridyl)-1-piperidylmethyl]piperidine (1.65 g) in ethyl acetate (25 ml) and the resulting suspension stirred at ambient temperature for 3 hours. Solvent was evaporated to give 4-[4-(4-pyridyl)-1-piperidylmethyl]piperidine trihydrochloride (1.60 g) as a colourless foam.

1. customSolvent was evaporated