Triphenylphosphine → HCID 18327890, compound

HRID 1250282Notes

Reaction equation

HRID 1250282 reaction equation
[N:1]([CH2:4][C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][C:6]=1[CH3:13])=[N+]=[N-].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C1(P(=O)(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>C(O)C.O>[NH2:1][CH2:4][C:5]1[CH:12]=[CH:11][C:8]([C:9]#[N:10])=[CH:7][C:6]=1[CH3:13]

Participants

6

Reactant 3

HCID 11776TriphenylphosphineHCID 13097Triphenylphosphine OxideHCID 18327893HCID 18327893, compound

Product 1

HCID 18327890HCID 18327890, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

The sub-title compound was prepared according to the method described in Example 1(ii) above from 1.4 g (8.1 mmol) of 4-azidomethyl-3-methylbenzonitrile (from step (iv) above) and 2.3 g (9.0 mmol) of triphenylphosphine in 18 mL of ethanol and 2 mL of water. Yield: 0.60 g (contaminated by triphenylphosphine oxide; estimated actual yield: 0.36 g (28%)).

Sources & evidence

ORD record
ord-adf0e9e5fcc44282abfc735fd0a15dc7
Source dataset
uspto-grants-2002_01
Patent number
US06337394B2

Reaction notes

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