反应详情

After boiling 2.5 g of 3-nitrobenzylideneacetoacetic acid methyl ester and 1.92 g of N-ethyl-4-amino-2-oxo-3-butenesulfonamide in a mixture of 10 ml of isopropanol and 5 ml of dimethylformamide for 6 hours there were obtained 2.2 g of 5-[(ethylsulfamoyl)acetyl]-1,4-dihydro-2-methyl-4-(3-nitrophenyl)nicotinic acid methyl ester of melting point 185°-187° (yellow crystalline powder from acetonitrile).