Hydrochloric Acid → HCID 68508069, compound

HRID 1256906Notes

Reaction equation

HRID 1256906 reaction equation
[Cl:1][C:2]1[CH:32]=[CH:31][C:5]([CH2:6][CH:7]([C:15]([NH:17][S:18]([C:21]2[CH:30]=[CH:29][C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:22]=2)(=[O:20])=[O:19])=[O:16])[C:8](N(CC)CC)=[O:9])=[CH:4][CH:3]=1.Cl.C(OCC)(=[O:36])C>>[Cl:1][C:2]1[CH:32]=[CH:31][C:5]([CH2:6][CH:7]([C:15]([NH:17][S:18]([C:21]2[CH:30]=[CH:29][C:28]3[C:23](=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:22]=2)(=[O:20])=[O:19])=[O:16])[C:8]([OH:36])=[O:9])=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 86645219HCID 86645219, compound

Product 1

HCID 68508069HCID 68508069, compound

Procedure

To the compound (2.10 g) obtained in Example 110 (4) were added 0.5 mol/L hydrochloric acid (40 ml) and ethyl acetate (80 mL), and the organic layer was collected by partitioning and washed with brine. The organic layer was concentrated under reduced pressure to give the title compound (1.90 g) as a white solid.

Workup

  1. customthe organic layer was collected
  2. customby partitioning
  3. washwashed with brine
  4. concentrationThe organic layer was concentrated under reduced pressure

Sources & evidence

ORD record
ord-0c6c56b6d5784a5181f83d5b4ab8d006
Source dataset
uspto-grants-2013_06
Patent number
US08461209B2

Reaction notes

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