反应详情

Into a reaction vessel were charged 83.1 parts of 2-methyl-2-adamantanol and 101 parts of triethylamine, and 200 parts of methyl isobutyl ketone was added thereto to form a solution. To this solution was added dropwise 78.4 parts of methacryloyl chloride (1.5 male based on 2-methyl-2-adamantanol). The solution was stirred at room temperature for about 10 hours. After filtration, the organic layer was washed with 5% aqueous sodium hydrogen carbonate solution and then washed twice with water. The organic layer was concentrated and distilled under reduced pressure to give 2-methyl-2-adamantyl methacrylate represented by the following formula in 75% yield:

1. additionwas added
2. customto form a solution
3. filtrationAfter filtration
4. washthe organic layer was washed with 5% aqueous sodium hydrogen carbonate solution
5. washwashed twice with water
6. concentrationThe organic layer was concentrated
7. distillationdistilled under reduced pressure