Diethyl Ether → 1-(1,4-Dioxaspiro[4,5]dec-8-ylacetyl)-4-(2-pyridinyl)piperazine
Reaction equation
[CH2:42]([Cl:43])[Cl:44].[CH3:15][CH2:16][N:17]([CH2:18][CH3:19])[CH2:20][CH3:21].[CH3:45][CH2:46][O:47][CH2:48][CH3:49].[Cl:22][C:23]([O:24][CH2:25][CH:26]([CH3:27])[CH3:28])=[O:29].[O:1]1[CH2:2][CH2:3][O:4][C:5]12[CH2:6][CH2:7][CH:8]([CH2:11][C:12](=[O:13])[OH:14])[CH2:9][CH2:10]2.[n:30]1[c:31]([N:36]2[CH2:37][CH2:38][NH:39][CH2:40][CH2:41]2)[cH:32][cH:33][cH:34][cH:35]1>>[O:1]1[CH2:2][CH2:3][O:4][C:5]12[CH2:6][CH2:7][CH:8]([CH2:11][C:12](=[O:14])[N:39]1[CH2:38][CH2:37][N:36]([c:31]3[n:30][cH:35][cH:34][cH:33][cH:32]3)[CH2:41][CH2:40]1)[CH2:9][CH2:10]2Participants
7
Sources & evidence
- ORD record
- ord-0ba4604aa9f949c780d4052471c41358
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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