反应详情

Cyclohexadiene (80g) and 154 g of t-butyl acrylate were dissolved in 500 g of THF solvent. After reacting at 50° C. for 24 hours, the solvent was removed by rotary evaporator. The residue was distilled under reduced pressure to obtain 112 g of t-butyl bicyclo[2,2,2]oct -5-ene-2-carboxylate as a mixture of endo and exo (yield: 48%).

1. customthe solvent was removed by rotary evaporator
2. distillationThe residue was distilled under reduced pressure