反应详情

Cyclohexadiene (80 g) and 140 g of 2-hydroxyethyl acrylate were dissolved in 500 g of THF solvent. After reacting at 50° C. for 24 hours, the solvent was removed by rotary evaporator. The residue was distilled under reduced pressure to obtain 100 g of 2-hydroxyethyl bicyclo[2,2,2]oct-5-ene-2- carboxylate as a mixture of endo and exo (yield: 45%).

1. customthe solvent was removed by rotary evaporator
2. distillationThe residue was distilled under reduced pressure