Triethylamine → HCID 23452884, compound

HRID 1277589Notes

Reaction equation

HRID 1277589 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([CH:13]=[C:14]([C:19]([O:21][CH3:22])=[O:20])[C:15]=1[N+:16]([O-:18])=[O:17])[O:8][CH2:9][C:10](Cl)=[O:11])([O:3][CH3:4])=[O:2].[CH2:23]([NH:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[CH2:24][CH2:25][CH2:26][CH2:27][CH3:28].C(N(CC)CC)C>O1CCCC1>[C:1]([C:5]1[CH:6]=[C:7]([CH:13]=[C:14]([C:19]([O:21][CH3:22])=[O:20])[C:15]=1[N+:16]([O-:18])=[O:17])[O:8][CH2:9][C:10]([N:29]([CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])=[O:11])([O:3][CH3:4])=[O:2]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 8920DihexylamineHCID 23452885HCID 23452885, compound

Product 1

HCID 23452884HCID 23452884, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

A stirred solution of (3,5-dicarbomethoxy-4-nitrophenoxy)acetyl chloride in tetrahydrofuran, cooled in an ice bath, is treated dropwise with a tetrahydrofuran solution containing 1 equivalent each of dihexylamine and triethylamine. After the addition, the precipitated amino hydrochloride is removed by filtration and the tetrahydrofuran filtrate is concentrated under reduced pressure to an oil which is used directly in the next step.

Workup

  1. additionAfter the addition
  2. customthe precipitated amino hydrochloride is removed by filtration
  3. concentrationthe tetrahydrofuran filtrate is concentrated under reduced pressure to an oil which

Sources & evidence

ORD record
ord-4ae86483c4c845c2b8b2e85778bf9860
Source dataset
uspto-grants-1981_07
Patent number
US04278598

Reaction notes

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