Ammonium Hydroxide → 4-Iodobenzamide

HRID 1277913Notes

Reaction equation

HRID 1277913 reaction equation
[OH-].[NH4+:2].[I:3][C:4]1[CH:12]=[CH:11][C:7]([C:8](Cl)=[O:9])=[CH:6][CH:5]=1>CCOCC>[I:3][C:4]1[CH:12]=[CH:11][C:7]([C:8]([NH2:2])=[O:9])=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 14923Ammonium HydroxideHCID 743734-Iodobenzoyl chloride

Product 1

HCID 775614-Iodobenzamide

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A total of 20 ml of 15 M ammonium hydroxide was reacted with a solution of 5.4 g p-iodobenzoyl chloride in 25 ml of ether. The crude product was recovered as described in Example 3 and recrystallized from ethanol to yield 3.5 g of p-iodobenzamide as white crystals, m.p. 221°-223°, Rf 0.46.

Workup

  1. customThe crude product was recovered
  2. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-6c756c1f5d264869a504fa0636545a07
Source dataset
uspto-grants-1981_07
Patent number
US04279887

Reaction notes

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