反应详情

Serinol (3.42 g) was added to a solution of trityl chloride (8.36 g) and triethylamine in 75 mL of dry DMF. After stirring at room temperature overnight, the reaction was poured into water and extracted twice with toluene. The combined organic layers were dried over potassium carbonate and concentrated to dryness. Recrystallization from boiling 1:1 benzene/hexane (two crops) afforded N-triphenylmethylserinol (7.59 g).

1. extractionextracted twice with toluene
2. dry with materialThe combined organic layers were dried over potassium carbonate
3. concentrationconcentrated to dryness
4. customRecrystallization