Hydrochloric Acid → HCID 178421583, compound

HRID 1283252Notes

Reaction equation

HRID 1283252 reaction equation
O=[C:2]([C:21]1[NH:25][N:24]=[N:23][N:22]=1)[O:3][C:4]1[CH:5]=[C:6]2[C:10](=[C:11]([Cl:14])[C:12]=1[Cl:13])[CH2:9][C:8]([CH:16]1[CH2:20][CH2:19][CH2:18][CH2:17]1)([CH3:15])[CH2:7]2.Cl.[NH2:27][OH:28].Cl>N1C=CC=CC=1>[N:27](=[C:2]([O:3][C:4]1[CH:5]=[C:6]2[C:10](=[C:11]([Cl:14])[C:12]=1[Cl:13])[CH2:9][C:8]([CH:16]1[CH2:17][CH2:18][CH2:19][CH2:20]1)([CH3:15])[CH2:7]2)[C:21]1[NH:22][N:23]=[N:24][N:25]=1)[OH:28]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 443297Hydroxyamine hydrochlorideHCID 178421584HCID 178421584, compound

Product 1

HCID 178421583HCID 178421583, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

A stirred solution of (1-oxo-2-cyclopentyl-2-methyl-6,7-dichloro-5-indanyloxymethyl)tetrazole (5.7 g., 0.015 mole) and hydroxylamine hydrochloride (3.2 g., 0.045 mole) in pyridine (60 ml.) is heated at 95°C. on a steam bath for 30 hours then poured into aqueous hydrochloric acid affording 5-(1-hydroximino-2-cyclopentyl-2-methyl-6,7-dichloro-5-indanyloxymethyl)tetrazole.

Sources & evidence

ORD record
ord-1d8b83055284418c85d493d9f5003ca0
Source dataset
uspto-grants-1976_08
Patent number
US03974212

Reaction notes

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