反应详情

To a solution of benzoic acid (1.22 g) and triethylamine (2.8 ml) in dry tetrahydrofuran (20 ml), 2-ethoxycarbonyloxyimino-2-cyanoacetic acid amide (1.85 g) is added at room temperature while stirring, and the resulting mixture is stirred at room temperature for 2 hours. The reaction mixture is admixed with water and extracted with ethyl acetate. The extract is washed with water, an aqueous solution of sodium hydrogencarbonate, 1 N hydrochloric acid and water in order, dried and concentrated to give ethyl benzoate (1.3 g) as an oil.

1. stirringthe resulting mixture is stirred at room temperature for 2 hours
2. extractionextracted with ethyl acetate
3. washThe extract is washed with water
4. dry with materialan aqueous solution of sodium hydrogencarbonate, 1 N hydrochloric acid and water in order, dried
5. concentrationconcentrated