Phenyl Isothiocyanate → HCID 13423327, compound

HRID 1284471Notes

Reaction equation

HRID 1284471 reaction equation
[C:1]1(/[C:7](/[C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[CH:8]\[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][OH:14])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:21]1([N:27]=[C:28]=[S:29])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>C(N(CC)CC)C>[C:21]1([NH:27][C:28]([O:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]/[CH:8]=[C:7](\[C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)/[C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[S:29])[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1

Participants

4

Reactant 2

HCID 7673Phenyl IsothiocyanateHCID 13417327HCID 13417327, compound

Product 1

HCID 13423327HCID 13423327, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

In the presence of triethylamine, (E)-7-phenyl-7-(3-pyridyl)-6-hepten-1-ol (2.0 g, 7.4 mmoles) was reacted with phenyl isothiocyanate (1.0 g, 7.5 mmoles) in the same manner as Example 9 to give 1-phenylaminothiocarbonyloxy-(E)-7-phenyl-7-(3-pyridyl)-6-heptene (Compound Id-28, 2.2 g) as crystals.

Sources & evidence

ORD record
ord-6fcf2f84acc04b1ba19b731ef9c6ddc5
Source dataset
uspto-grants-1986_01
Patent number
US04563446

Reaction notes

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