Phenol → Phenol

HRID 1286566Notes

Reaction equation

HRID 1286566 reaction equation
Brc1cccnc1.Oc1ccccc1>C1CCC2=NCCCN2CC1.COc1ccc(OC)c([P](C2CCCCC2)(C2CCCCC2)->[Pd]2(<-[NH2]c3ccccc3-c3cccc[c]32)[O]S(C)(=O)=O)c1-c1c(C(C)C)cc(C(C)C)cc1C(C)C.CS(C)=O>c1ccc(Oc2cccnc2)cc1

Participants

9

Reactant 2

HCID 996PhenolHCID 122863-Bromopyridine

Product 4

HCID 996PhenolHCID 7095BiphenylHCID 122863-BromopyridineHCID 2005103-Phenoxypyridine

Reagents, catalysts & solvents 3

HCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneReagentHCID 178492615HCID 178492615, compoundReagentHCID 679Dimethyl SulfoxideSolvent4×

Procedure

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Workup

  1. additionNo procedure recorded
  2. aliquotNo procedure recorded
  3. additionNo procedure recorded

Sources & evidence

ORD record
ord-26aa839e2f2a4ff9b1747f2e9351f9af
Source dataset
HTE Pd-catalyzed cross-coupling screen
Original link
View source

Reaction notes

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