Ethyl Lactate → HCID 53670576, compound

HRID 1287356Notes

Reaction equation

HRID 1287356 reaction equation
[CH2:1]([O:3][C:4](=[O:8])[CH:5]([CH3:7])[OH:6])[CH3:2].[Br:9][CH2:10][CH2:11][CH2:12][CH2:13]Br.[H-].[Na+]>C1COCC1>[CH2:1]([O:3][C:4](=[O:8])[CH:5]([CH3:7])[O:6][CH2:13][CH2:12][CH2:11][CH2:10][Br:9])[CH3:2]

Participants

5

Reactant 3

HCID 7344Ethyl LactateHCID 80561,4-DibromobutaneHCID 24758Sodium hydride

Product 1

HCID 53670576HCID 53670576, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The lactic acid ethyl ester and 1,4-dibromo-butane were reacted in THF in the presence of NaH to obtain 7-bromo-2-methyl-3-oxaheptanoic acid ethyl ester and subsequently, the exchange of bromine and iodine was carried out, as described in 4(d).

Sources & evidence

ORD record
ord-cdb7f651793b497ca7b1edb4335e92d8
Source dataset
uspto-grants-1976_10
Patent number
US03984459

Reaction notes

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