4-Chlorophenyl isothiocyanate → HCID 178483422, compound

HRID 1287412Notes

Reaction equation

HRID 1287412 reaction equation
[Na].Cl.Cl.CN(C)CCCCCCCCCCC(N)=N.ClC1C=CC(N=C=S)=CC=1.Cl.Cl.[Cl:32][C:33]1[CH:38]=[CH:37][C:36]([NH:39][C:40]([NH:42][C:43](=[NH:57])[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][N:54]([CH3:56])[CH3:55])=[S:41])=[CH:35][CH:34]=1>C(O)(C)C.CC(C)=O>[Cl:32][C:33]1[CH:34]=[CH:35][C:36]([NH:39][C:40]([NH:42][C:43](=[NH:57])[CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][N:54]([CH3:56])[CH3:55])=[S:41])=[CH:37][CH:38]=1

Participants

7

Reactant 4

HCID 164804-Chlorophenyl isothiocyanateHCID 5360545SodiumHCID 21508022HCID 21508022, compoundHCID 178483423HCID 178483423, compound

Product 1

HCID 178483422HCID 178483422, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolvent2×HCID 3776IsopropanolSolvent

Procedure

Following a procedure similar to that described in Example 42 but using 2.8 g. sodium in 300 ml. dry acetone, 18.5 g. 11-(dimethylamino)undecanamidine dihydrochloride, and 11.9 g. 4-chlorophenyl isothiocyanate in 100 ml. dry acetone there was obtained 10.4 g. 1-(4-chlorophenyl)-3-[11-(dimethylamino)undecanimidoyl]-2-thiourea dihydrochloride; m.p. 130°-132°C. (from isopropyl alcohol).

Sources & evidence

ORD record
ord-f72f554cb4b74c33b655fdb1c1ff6301
Source dataset
uspto-grants-1976_10
Patent number
US03984467

Reaction notes

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