反应详情

A solution of n-butyllithium was added dropwise to a stirred, cooled (-78° C.) solution of compound of step 2.1 in dry THF. The mixture was maintained under these conditions for 40 mins and then poured into a slurry of dry ether and cardice. The solution was acidified with 36% HCl, washed with water and dried (magnesium sulphate). The solvent was removed to yield a white solid.

1. temperatureThe mixture was maintained under these conditions for 40 mins
2. washwashed with water
3. dry with materialdried (magnesium sulphate)
4. customThe solvent was removed
5. customto yield a white solid