反应详情

A solution of 105 mg (0.42 mmol) of the product of Step A in 10 mL of dry THF was treated with 17 mg (0.43 mmol) of 60% NaH in oil dispersion at 0° C. for 1 h. TLC analysis indicated starting material was present and 2 mL of DMF was added. After 1.5 h. at 0° C., the solvent was evaporated and the mixture was worked up in the standard to give 90 mg of product.

1. customthe solvent was evaporated