Potassium Carbonate → HCID 17755864, compound

HRID 1294081Notes

Reaction equation

HRID 1294081 reaction equation
[N+:1]([C:4]1[CH:10]=[C:9]([OH:11])[CH:8]=[CH:7][C:5]=1[NH2:6])([O-])=O.Cl[C:13]1[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][N:14]=1.C([O-])([O-])=O.[K+].[K+]>CN(C=O)C.CO.[Pd]>[NH2:19][C:16]1[CH:17]=[CH:18][C:13]([O:11][C:9]2[CH:8]=[CH:7][C:5]([NH2:6])=[C:4]([NH2:1])[CH:10]=2)=[N:14][CH:15]=1

Participants

7

Reactant 3

HCID 11430Potassium CarbonateHCID 783082-Chloro-5-nitropyridineHCID 37588824-Amino-3-Nitrophenol

Product 1

HCID 17755864HCID 17755864, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

2-Nitro-4-hydroxyaniline was reacted with 2-chloro-5-nitropyridine and K2CO3 in DMF at rt, followed by hydrogenation over Pd/C in MeOH, afforded the title compound; MS m/e 217 (M+1).

Sources & evidence

ORD record
ord-36746e833c704596986dcc9ee71cbe81
Source dataset
uspto-grants-2007_07
Patent number
US07238813B2

Reaction notes

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