4-Chlororesorcinol → HCID 58913671, compound

HRID 1296884Notes

Reaction equation

HRID 1296884 reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([OH:6])=[CH:4][C:3]=1[OH:9].[CH2:10]([O:12][C:13]1[CH:14]=[C:15]([C:19]2[CH:24]=[CH:23][C:22]([CH2:25][C:26]([OH:28])=O)=[CH:21][CH:20]=2)[CH:16]=[CH:17][CH:18]=1)[CH3:11].P(Cl)(Cl)(Cl)(Cl)Cl.[CH3:35]N(C=O)C>CCCCCC.C(OCC)(=O)C>[Cl:1][C:2]1[CH:8]=[C:7]2[C:5](=[CH:4][C:3]=1[OH:9])[O:6][CH:35]=[C:25]([C:22]1[CH:21]=[CH:20][C:19]([C:15]3[CH:16]=[CH:17][CH:18]=[C:13]([O:12][CH2:10][CH3:11])[CH:14]=3)=[CH:24][CH:23]=1)[C:26]2=[O:28]

Participants

6

Reactant 4

HCID 17314-ChlororesorcinolHCID 6228DimethylformamideHCID 24819Phosphorus pentachlorideHCID 2758741(3'-Ethoxy-biphenyl-4-yl)-acetic acid

Product 1

HCID 58913671HCID 58913671, compound

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

This compounds was synthesised in the same manner as described above. 4-Chlororesorcinol (0.26 g, 1.8 mmol), (3′-Ethoxybiphenyl-4-yl)-acetic acid (0.44 g, 1.8 mmol), BF3Et2O (5 ml), PCl5 (0.56 g, 2.69 mmol), DMF (8 ml and 5 ml). The crude oil product (0.39 g, 55.2%) was taken onto the next stage. Rf 0.8 ethyl acetate/hexane (70/30)].

Workup

  1. customThis compounds was synthesised in the same manner

Sources & evidence

ORD record
ord-c9aff849d4a742f0afe6e67ef5964e6a
Source dataset
uspto-grants-2007_07
Patent number
US07247734B2

Reaction notes

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