4-Chlororesorcinol → HCID 58913645, compound

HRID 1296887Notes

Reaction equation

HRID 1296887 reaction equation
[Cl:1][C:2]1[CH:8]=[CH:7][C:5]([OH:6])=[CH:4][C:3]=1[OH:9].[CH3:10][O:11][C:12]1[CH:13]=[C:14]([C:20]2[CH:25]=[CH:24][CH:23]=[C:22]([CH2:26][C:27]([OH:29])=O)[CH:21]=2)[CH:15]=[CH:16][C:17]=1[O:18][CH3:19].P(Cl)(Cl)(Cl)(Cl)Cl.[CH3:36]N(C=O)C>>[Cl:1][C:2]1[CH:8]=[C:7]2[C:5](=[CH:4][C:3]=1[OH:9])[O:6][CH:36]=[C:26]([C:22]1[CH:21]=[C:20]([C:14]3[CH:15]=[CH:16][C:17]([O:18][CH3:19])=[C:12]([O:11][CH3:10])[CH:13]=3)[CH:25]=[CH:24][CH:23]=1)[C:27]2=[O:29]

Participants

5

Reactant 4

HCID 17314-ChlororesorcinolHCID 6228DimethylformamideHCID 24819Phosphorus pentachlorideHCID 22225974HCID 22225974, compound

Product 1

HCID 58913645HCID 58913645, compound

Procedure

This compounds was synthesised in the same manner as described above. 4-Chlororesorcinol (0.15 g, 1.0 mmol), (3′,4′-dimethoxy-biphenyl-3-yl)-acetic acid (0.28 g, 1 mmol), BF3Et2O (5 ml), PCl5 (0.32 g, 1.5 mmol), DMF (6 ml and 4 ml). The white precipitate formed was shown to contain the required compound and was taken directly onto the next stage.

Workup

  1. customThis compounds was synthesised in the same manner
  2. customThe white precipitate formed

Sources & evidence

ORD record
ord-9fb7ee51c9c44b5a9c64d59d8d97354b
Source dataset
uspto-grants-2007_07
Patent number
US07247734B2

Reaction notes

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