HRID130036

反应详情

EQUATION

反应方程式

HRID 130036 的结构方程式

REACTANTS

反应物

2

结构：Fc1ccccc1Br

Benzene, 1-bromo-2-fluoro-

C6H4BrF

结构：Cn1cnc(C#N)c1

1-METHYL-1H-IMIDAZOLE-4-CARBONITRILE

C5H5N3

PRODUCTS

生成物

2

结构：CC(C)(C)c1ccc(-c2ccc(C(C)(C)C)cc2)cc1

4,4'-Di-tert-butylbiphenyl

C20H26

结构：Cn1cnc(C#N)c1-c1ccccc1F

未命名化合物

收率 5.79%

AUXILIARIES

试剂、催化剂与溶剂

5

结构：CC(=O)[O-].[K+]

试剂HCID517044

Potassium acetate

C2H3KO2

结构：C=C[CH2-].C=C[CH2-].[Cl][Pd+].[Cl][Pd+]

催化剂HCID61538

未命名化合物

结构：c1ccc(P(c2ccccc2)C2CCCCC2)cc1

催化剂HCID80756

Phosphine, cyclohexyldiphenyl-

C18H21P

结构：Cc1ccc(C)cc1

p-Xylene

C8H10

结构：CC(C)(C)c1ccc(-c2ccc(C(C)(C)C)cc2)cc1

内标HCID74195

4,4'-Di-tert-butylbiphenyl

C20H26

CONDITIONS

反应条件

温度: 120 °C

WORKUP

后处理

additionThe plate was removed from the glovebox, opened, and diluted to a 900 uL total volume with N,N-dimethylacetamide. The plate was stirred for 5 min and a 75 uL sample was taken and filtered into an HPLC analysis plate. The filter was rinsed with 400 uL acetonitrile/water (4:1) solution and analyzed by UHPLCMS
stirring未记录说明
aliquot未记录说明
filtration保留 organic