Sodium ion → 1-[3-(2,3-Dihydro-1,4-benzodioxin-2-yl)propyl]-4-phenylpiperidin-4-ol

HRID 133865Notes

Reaction equation

HRID 133865 reaction equation
[Al+3:29].[CH3:34][CH2:35][O:36][C:37](=[O:38])[CH3:39].[H-:28].[H-:31].[H-:32].[H-:33].[Li+:30].[Na+:41].[O:1]1[CH:2]([CH2:11][CH2:12][C:13](=[O:14])[N:15]2[CH2:16][CH2:17][C:18]([c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)([OH:27])[CH2:19][CH2:20]2)[CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][cH:9][cH:10]2.[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1.[OH-:40].[OH2:47]>>[O:1]1[CH:2]([CH2:11][CH2:12][CH2:13][N:15]2[CH2:16][CH2:17][C:18]([c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)([OH:27])[CH2:19][CH2:20]2)[CH2:3][O:4][c:5]2[c:6]1[cH:7][cH:8][cH:9][cH:10]2

Participants

10

Reactant 9

HCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 21331974HCID 21331974, compound

Product 1

HCID 213319551-[3-(2,3-Dihydro-1,4-benzodioxin-2-yl)propyl]-4-phenylpiperidin-4-ol

Sources & evidence

ORD record
ord-addecac21054463181024bb3073056dc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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