Acetonitrile → 4-[1-Ethyl-1-(3-methyl-4-trimethylsilanylethynyl-phenyl)-propyl]-2-methyl-phenol

HRID 134558Notes

Reaction equation

HRID 134558 reaction equation
[C:8](#[CH:9])[Si:10]([CH3:11])([CH3:12])[CH3:13].[CH2:14]([CH3:15])[C:16]([CH2:17][CH3:18])([c:19]1[cH:20][c:21]([CH3:26])[c:22]([OH:25])[cH:23][cH:24]1)[c:27]1[cH:28][c:29]([CH3:41])[c:30]([O:33][S:34]([C:35]([F:36])([F:37])[F:38])(=[O:39])=[O:40])[cH:31][cH:32]1.[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[CH3:42][C:43]#[N:44].[Cu:45][I:46].[cH:47]1[cH:48][cH:49][c:50]([P:51]([Pd:52]([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)([c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)([P:72]([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)([c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)[P:91]([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)([c:110]2[cH:111][cH:112][cH:113][cH:114][cH:115]2)[c:116]2[cH:117][cH:118][cH:119][cH:120][cH:121]2)[cH:122][cH:123]1>>[C:8](#[C:9][c:30]1[c:29]([CH3:41])[cH:28][c:27]([C:16]([CH2:14][CH3:15])([CH2:17][CH3:18])[c:19]2[cH:20][c:21]([CH3:26])[c:22]([OH:25])[cH:23][cH:24]2)[cH:32][cH:31]1)[Si:10]([CH3:11])([CH3:12])[CH3:13]

Participants

7

Reactant 6

HCID 6342AcetonitrileHCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 58598300Trifluoromethanesulfonic acid 4-[1-ethyl-1-(4-hydroxy-3-methyl-phenyl)-propyl]-2-methyl-phenyl esterHCID 178420554HCID 178420554, compound

Product 1

HCID 585983194-[1-Ethyl-1-(3-methyl-4-trimethylsilanylethynyl-phenyl)-propyl]-2-methyl-phenol

Sources & evidence

ORD record
ord-feba6afc78034c829962ea74c5f3b328
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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