反应详情

6.65 g of the compound obtained in Step 3 and 4.6 ml of hydrazine monohydrate were added to 100 ml of n-propanol. The resulting mixture was refluxed for 6 hours, and distilled under a reduced pressure to remove the solvent. The residue thus obtained was dissolved in 80 ml of chloromethane, washed with water, and dried over anhydrous magnesium sulfate. The resulting organic layer was concentrated under a reduced pressure to obtain 6.20 g (yield: 85.6%) of the title compound.

1. temperatureThe resulting mixture was refluxed for 6 hours
2. distillationdistilled under a reduced pressure
3. customto remove the solvent
4. customThe residue thus obtained
5. washwashed with water
6. dry with materialdried over anhydrous magnesium sulfate
7. concentrationThe resulting organic layer was concentrated under a reduced pressure