反应详情

As described for 78, 2-methoxycarbonyl cycloheptyl amine, 4-nitrophenyl chloroformate, diisopropyl(ethyl)amine, and 7-chloro-4-(1-piperazinyl)-2-quinolinamine are reacted to afford the product. LC-MS: 460 (M++1). 1H NMR (CDCl3) δ 7.72 (d, 1H), 7.60 (s, 1H), 7.18 (d, 1H), 6.15 (s, 1H), 5.50 (d, 1H), 4.70 (s, 2H), 4.15 (m, 1H), 3.70 (s, 3H), 3.60 (m, 4H), 3.10 (m, 4H), 2.95 (m, 1H), 2.00 (m, 1H), 1.85 (m, 3H), 1.65 (m, 5H), 1.45 (m, 1H).

1. customare reacted
2. customto afford the product