Acetonitrile → 5-(2-Butoxy-5-trimethylsilylethynyl-3-pyridinyl)-3-ethyl-2-(2-methoxy-ethyl)-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
Reaction equation
[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][c:6]1[n:7][cH:8][c:9]([I:28])[cH:10][c:11]1-[c:12]1[nH:13][c:14](=[O:27])[c:15]2[c:16]([n:17]1)[c:18]([CH2:25][CH3:26])[n:19]([CH2:21][CH2:22][O:23][CH3:24])[n:20]2.[CH3:29][Si:30]([CH3:31])([CH3:32])[C:33]#[CH:34].[CH3:35][C:36]#[N:37].[CH3:39][CH2:40][N:41]([CH2:42][CH3:43])[CH2:44][CH3:45].[I-:38].[Pd:46]([Cl:47])[Cl:48].[c:49]1([P:50]([c:51]2[cH:52][cH:53][cH:54][cH:55][cH:56]2)[c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)[cH:63][cH:64][cH:65][cH:66][cH:67]1.[c:68]1([P:69]([c:70]2[cH:71][cH:72][cH:73][cH:74][cH:75]2)[c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)[cH:82][cH:83][cH:84][cH:85][cH:86]1>>[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][c:6]1[n:7][cH:8][c:9]([C:34]#[C:33][Si:30]([CH3:29])([CH3:31])[CH3:32])[cH:10][c:11]1-[c:12]1[nH:13][c:14](=[O:27])[c:15]2[c:16]([n:17]1)[c:18]([CH2:25][CH3:26])[n:19]([CH2:21][CH2:22][O:23][CH3:24])[n:20]2Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-8b83c85956a34efe9c539772476cc291
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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