Hydrochloric Acid → 2-Hydroxy-N-methyl-N-{2-[(4-{3-methyl-4-(pyridin-2-ylmethoxy)anilino}quinazolin-5-yl)oxy]ethyl}acetamide
Reaction equation
[C:38](=[O:39])([O-:40])[O-:41].[ClH:29].[K+:42].[K+:43].[O:44]1[CH2:45][CH2:46][O:47][CH2:48][CH2:49][O:50][CH2:51][CH2:52][O:53][CH2:54][CH2:55][O:56][CH2:57][CH2:58][O:59][CH2:60][CH2:61]1.[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[OH:1][CH2:2][C:3](=[O:4])[N:5]([CH3:6])[CH2:7][CH2:8][O:9][c:10]1[c:11]2[c:12]([NH:20][c:21]3[cH:22][c:23]([CH3:28])[c:24]([OH:27])[cH:25][cH:26]3)[n:13][cH:14][n:15][c:16]2[cH:17][cH:18][cH:19]1.[c:30]1([CH2:36][Cl:37])[cH:31][cH:32][cH:33][cH:34][n:35]1>>[OH:1][CH2:2][C:3](=[O:4])[N:5]([CH3:6])[CH2:7][CH2:8][O:9][c:10]1[c:11]2[c:12]([NH:20][c:21]3[cH:22][c:23]([CH3:28])[c:24]([O:27][CH2:36][c:30]4[cH:31][cH:32][cH:33][cH:34][n:35]4)[cH:25][cH:26]3)[n:13][cH:14][n:15][c:16]2[cH:17][cH:18][cH:19]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-98b97e9b8072434299fb193cd62da927
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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