2-Acetylfuran → HCID 18507351, compound

HRID 1355839Notes

Reaction equation

HRID 1355839 reaction equation
[C:1]([C:4]1O[CH:6]=[CH:7][CH:8]=1)(=O)[CH3:2].COC(OC)N(C)C.[C:17](=[O:20])(O)O.[NH2:21][C:22]([NH2:24])=[NH:23].C[O-].[Na+].[Cl:28]N1C(=O)CCC1=O>CN(C=O)C.CO.C(O)(=O)C>[Cl:28][C:1]1[C:4]([C:8]2[O:20][CH:17]=[CH:6][CH:7]=2)=[N:23][C:22]([NH2:24])=[N:21][CH:2]=1

Participants

9

Reactant 5

HCID 145052-AcetylfuranHCID 31398ChlorosuccinimideHCID 78373Dimethylformamide dimethyl acetalHCID 286947Carbonic acid-guanidine (1:1)HCID 10942334Sodium Methoxide

Product 1

HCID 18507351HCID 18507351, compound

Reagents, catalysts & solvents 3

HCID 176Acetic AcidSolventHCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

From 2-acetylfuran and N,N-dimethylformamide dimethyl acetal in DMF. Then treatment with guanidine carbonate and sodium methylate in methanol. Then treatment with N-chlorosuccinimide in acetic acid. EI-MS m/e (%): 197 (M{37Cl}+, 32), 195 (M{35Cl}+, 100).

Sources & evidence

ORD record
ord-c2b4bab2ebdc403692f1eeafa5778234
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

Loading…