Isopropanol → HCID 18507596, compound

HRID 1355935Notes

Reaction equation

HRID 1355935 reaction equation
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[C:11]([I:12])=[C:10](S(C)=O)[N:9]=[C:8]([NH2:16])[N:7]=1.[CH:17]([OH:20])([CH3:19])[CH3:18].C1CCN2C(=NCCC2)CC1>C1COCC1>[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[C:11]([I:12])=[C:10]([O:20][CH:17]([CH3:19])[CH3:18])[N:9]=[C:8]([NH2:16])[N:7]=1

Participants

5

Reactant 3

HCID 3776IsopropanolHCID 811841,8-Diazabicyclo(5.4.0)undec-7-eneHCID 18507211HCID 18507211, compound

Product 1

HCID 18507596HCID 18507596, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

From 4-furan-2-yl-5-iodo-6-methanesulfinyl-pyrimidin-2-yl-amine, isopropanol and DBU in THF. ES-MS m/e (%): 346 (M+H+, 100).

Sources & evidence

ORD record
ord-f44e0e6156144fe6b178cc6adbcb27a0
Source dataset
uspto-grants-2003_07
Patent number
US06586441B2

Reaction notes

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