Dimethylformamide → [4-[[(5-Bromopyrimidin-2-yl)amino]methyl]piperidin-1-yl]-(2-phenylcyclopropyl)methanone
Reaction equation
[Br:27][c:28]1[cH:29][n:30][c:31]([Cl:34])[n:32][cH:33]1.[C:35](=[O:36])([O-:37])[O-:38].[CH3:46][CH2:47][O:48][C:49](=[O:50])[CH3:51].[Cs+:39].[Cs+:40].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7].[O:41]=[CH:42][N:43]([CH3:44])[CH3:45].[c:8]1([CH:14]2[CH:15]([C:17](=[O:18])[N:19]3[CH2:20][CH2:21][CH:22]([CH2:25][NH2:26])[CH2:23][CH2:24]3)[CH2:16]2)[cH:9][cH:10][cH:11][cH:12][cH:13]1>>[c:8]1([CH:14]2[CH:15]([C:17](=[O:18])[N:19]3[CH2:20][CH2:21][CH:22]([CH2:25][NH:26][c:31]4[n:30][cH:29][c:28]([Br:27])[cH:33][n:32]4)[CH2:23][CH2:24]3)[CH2:16]2)[cH:9][cH:10][cH:11][cH:12][cH:13]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-85e9a52b731444ecac6a0577f2afe36b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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