Ammonia → HCID 178491700, compound

HRID 1374650Notes

Reaction equation

HRID 1374650 reaction equation
[CH3:1][O:2][C:3]1[CH:15]=[CH:14][C:6]([CH2:7][S:8][CH2:9][C:10](OC)=[O:11])=[CH:5][CH:4]=1.[CH:16](OCC)=O.[Na].[CH3:22][S:23][C:24](=[NH:26])[NH2:25].S([O-])([O-])(=O)=O.N>C(O)C.C(Cl)Cl.CO>[CH3:22][S:23][C:24]1[N:25]=[C:10]([OH:11])[C:9]([S:8][CH2:7][C:6]2[CH:14]=[CH:15][C:3]([O:2][CH3:1])=[CH:4][CH:5]=2)=[CH:16][N:26]=1

Participants

8

Reactant 5

HCID 222AmmoniaHCID 8025Ethyl formateHCID 5360545SodiumHCID 15626815HCID 15626815, compoundHCID 21115369HCID 21115369, compound

Product 1

HCID 178491700HCID 178491700, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 21226129Dichloromethane methanolSolvent

Procedure

Prepared from methyl 4-methoxybenzylsulphenyl-acetate and ethyl formate in the presence of sodium and subsequent reaction with S-methylisothiourea-sulphate in ethanol, Rf value: 0.4 (silica gel; methylene chloride/methanol/conc. aqueous ammonia=20:1:0.1)

Sources & evidence

ORD record
ord-7acc21edd9444c9f933ae87cc1097a05
Source dataset
uspto-grants-2007_01
Patent number
US07166599B2

Reaction notes

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